Her life ended with a triumphal tour of England, where she was treated as a visiting princess. She met James I, the Royal Family and the best of London society.
Before her ship left London, she contracted an unknown disease - possibly pneumonia, smallpox or tuberculosis. When it became apparent that she would not survive the voyage home to Virginia, she was taken ashore and died.
She was buried in a churchyard in Gravesend, aged only 21 or 22.